Co-reporter: Rongxian Bai, Ping Liu, Jian Yang, Changhui Liu, and Yanlong Gu
pp: 1292
Publication Date(Web):May 11, 2015
DOI: 10.1021/sc500763q
Substituted 2-aminothiophenes were synthesized through Gewald reaction by using an easily available solid base catalyst, sodium aluminate. Cost-effectiveness, mild and environmentally benign conditions, and excellent catalytic performance are the features of this system. Furthermore, the NaAlO2 catalyst can be swimmingly recovered and reused in this reaction.Keywords: 2-Aminothiophenes; Gewald reaction; Multicomponent reaction; NaAlO2