1-acetyloxycyclohexane-1-carboxylic Acid

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CAS: 6282-51-5
MF: C9H14O4
MW: 186.20506
Synonyms: 1-acetyloxycyclohexane-1-carboxylic Acid

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Jack D Henion

Cornell University
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Co-reporter: Hoang V. Le, Lijun Fan, Bruce Ganem
pp: 2209-2211
Publication Date(Web):27 April 2011
DOI: 10.1016/j.tetlet.2010.11.156
N-tert-Butylamides are readily converted into the corresponding carboxylic acids by simple nitrosation. The process, which occurs under mild nonaqueous conditions, leaves carboxylic esters untouched and transforms multicomponent reaction products into useful building blocks for further synthetic elaboration.Image for unlabelled figure