Nickel(0)-promoted carboxylation of aryl ynol ether proceeded in a highly regioselective manner to produce α-substituted-β-aryloxyacrylic acid derivatives. The α-substituted-β-aryloxyacrylic acids were transformed into the corresponding β-aryloxypropionic acid derivative as an optically active form via rhodium-catalyzed asymmetric hydrogenation.

The palladium-catalyzed silaboration of ynamides is demonstrated. The silaboration proceeds in a highly regioselective manner to give the corresponding tri- and tetrasubstituted enamide derivatives having both a silyl group and a boryl group on the alkene. Furthermore, the silaborated enamide could be utilized as a coupling partner in Suzuki–Miyaura coupling with aryl iodides to give the corresponding cross-coupling product in good yield.