Co-reporter:Jiaqin Wang, Jun Zhu, Ling Si, Qi Du, Hongli Li, Wentao Bi, David Da Yong Chen
Analytica Chimica Acta 2017 Volume 996(Volume 996) pp:
Publication Date(Web):15 December 2017
DOI:10.1016/j.aca.2017.10.007
•A high throughput screening method for the measurements of PCAs in water was successfully developed.•High efficiency extraction was achieved through DSPE using velvet-like graphitic carbon nitride.•DART-MS was employed for rapid and high throughput detection of PCAs after extraction.•The total time for a single sample analysis including all steps and operations is ∼ 10 min.A high throughput, low environmental impact methodology for rapid determination of phenoxy carboxylic acids (PCAs) in water samples was developed by combing dispersive solid phase extraction (DSPE) using velvet-like graphitic carbon nitride (V-g-C3N4) and direct analysis in real time mass spectrometry (DART-MS). Due to the large surface area and good dispersity of V-g-C3N4, the DSPE of PCAs in water was completed within 20 s, and the elution of PCAs was accomplished in 20 s as well using methanol. The eluents were then analyzed and quantified using DART ionization source coupled to a high resolution mass spectrometer, where an internal standard was added in the samples. The limit of detection ranged from 0.5 ng L−1 to 2 ng L−1 on the basis of 50 mL water sample; the recovery 79.9–119.1%; and the relative standard deviation 0.23%–9.82% (≥5 replicates). With the ease of use and speed of DART-MS, the whole protocol can complete within mere minutes, including sample preparation, extraction, elution, detection and quantitation. The methodology developed here is simple, fast, sensitive, quantitative, requiring little sample preparation and consuming significantly less toxic organic solvent, which can be used for high throughput screening of PCAs and potentially other contaminants in water.Download high-res image (230KB)Download full-size image
Co-reporter:Man Wang, Wentao Bi, Xiaohua Huang, David Da Yong Chen
Journal of Chromatography A 2016 Volume 1449() pp:8-16
Publication Date(Web):3 June 2016
DOI:10.1016/j.chroma.2016.04.044
•Ball mill assisted mechanochemical extraction is fast, reproducible, and with good yield.•Ionic liquid as co-solvent facilitates analyte concentration during extraction.•Extraction conditions are chemically mild, more suitable for hard plant matters.•Green extraction method without the use of volatile organic solvents.A ball mill assisted mechanochemical extraction method was developed to extract compounds of natural product (NP) from plant using ionic liquid (IL). A small volume ball mill, also known as PastPrep® Homogenizer, which is often used for high-speed lysis of biological samples and for other applications, was used to dramatically increase the speed, completeness and reproducibility of the extraction process at room temperature to preserve the chemical integrity of the extracted compounds. In this study, tanshinones were selected as target compounds to evaluate the performance of this extraction method. Factors affecting the extraction efficiency, such as the duration, IL concentration and solid/liquid ratio were systematically optimized using the response surface methodology. Under the optimized conditions, the described method was more efficient and much faster than the conventional extraction methods such as methanol based ultrasound assisted extraction (UAE) and heat reflux extraction (HRE) that consumes a lot more organic solvent. In addition, the natural products of interest were enriched by anion metathesis of ionic liquids, combining extraction and preconcentration in the same process. The extractant was analyzed by HPLC and LC–MS. The reproducibility (RSD, n = 5), correlation coefficient (r2) of the calibration curve, and the limit of detection, were determined to be in the range of 4.7–5.2%, 0.9992–0.9995, and 20–51 ng/mL, respectively.
Co-reporter:Man Wang, Jiaqin Wang, Yue Zhang, Qian Xia, Wentao Bi, Xiaodi Yang, David Da Yong Chen
Journal of Chromatography A 2016 Volume 1443() pp:262-266
Publication Date(Web):22 April 2016
DOI:10.1016/j.chroma.2016.03.061
•An fast environment-friendly extraction method was developed.•Tanshinones were selected as target compounds to evaluate the extraction method.•This research may fundamentally shape the future development of extraction.A fast environment-friendly extraction method, ball mill-assisted deep eutectic solvent-based extraction, was used for the extraction of natural products from plants. In this study, tanshinones were selected as target compounds to evaluate the efficiency of the developed extraction method. Under the optimized experimental conditions, cryptotanshinone (0.176 mg/g), tanshinone I (0.181 mg/g), and tanshinone II A (0.421 mg/g) were extracted from Salvia miltiorrhiza Bunge, and the developed method was found to be greener, more efficient, and faster than conventional, environmentally harmful extraction methods such as methanol-based ultrasound-assisted extraction and heat reflux extraction. The analytical performances including recovery, reproducibility (RSD, n = 5), correlation of determination (r2), and the limit of detection, with the ranges of 96.1–103.9%, 1.6–1.9%, 0.9973–0.9984, and 5–8 ng/mL, were respectively obtained. Application of ball mill-assisted deep eutectic solvent-based extraction may fundamentally shape the future development of extraction methods.
Co-reporter:Jing Yang, Huihui Chen, Junhua Gao, Tingting Yan, Fengya Zhou, Shihai Cui, Wentao Bi
Materials Letters 2016 Volume 164() pp:183-189
Publication Date(Web):1 February 2016
DOI:10.1016/j.matlet.2015.10.130
•Fe3O4/g-C3N4 nanocomposite was prepared via calcination and hydrothermal methods.•The material is used as the catalyst for 2,4,6-TCP degradation under visible light.•The degradation of 2,4,6-TCP obeys the pseudo-first-order kinetics.•The photocatalytic mechanism of Fe3O4/g-C3N4 nanocomposite was discussed.The novel, stable, and environment-friendly Fe3O4/g-C3N4 nanocomposites (10–15 nm) were synthesized with a combination of calcination and co-precipitation methods. The nanocomposites were characterized using transmission electron microscopy (TEM), X-ray diffraction (XRD), vibrating sample magnetometry (VSM), Fourier transform infrared spectroscopy (FT-IR), ultraviolet–visible (UV–vis) diffuse reflectance spectroscopy, thermogravimetric analysis (TGA), X-ray photoelectron spectroscopy (XPS), and Brunauer–Emmett–Teller analysis (BET). The results indicated that the Fe3O4 nanoparticles were uniformly deposited on the g-C3N4 nanosheets. The photocatalytic activity of the Fe3O4/g-C3N4 nanocomposites was investigated for the first time in terms of the photodegradation of 2,4,6-trichlorophenol (2,4,6-TCP) under visible light. The nanocomposites with 50% g-C3N4 (mass percent) were found to have good photocatalytic activity for the photodegradation of 2,4,6-TCP. In addition, the nanocomposites could be reused several times by applying an external magnetic field to separate them from the solution. The photodegradation kinetics and a possible reaction mechanism were investigated. Hydroxyl radicals were detected during the photodegradation reactions by using fluorescence spectroscopy.
Co-reporter:Xinru Ding, Jun Zhu, Yue Zhang, Qian Xia, Wentao Bi, Xiaodi Yang, Jinfei Yang
Talanta 2016 Volume 154() pp:119-126
Publication Date(Web):1 July 2016
DOI:10.1016/j.talanta.2016.03.065
•A velvet-like graphitic carbon nitride with large surface area was prepared.•It was utilized for fast dispersive solid phase extraction of flavonoids.•Significant variables were investigated using the response surface methodology.Well-dispersed velvet-like graphitic carbon nitride nanoparticles with a large surface area were prepared and utilized for separation and concentration of bioactive compounds from fruit extracts by fast (20 s) forced adsorption. The large surface area, enhanced non-covalent interactions of this nanoparticle with bioactive compounds and good dispersity in different solvents benefited its application as a good sorbent. To evaluate their adsorption capabilities, these carbon nitride nanoparticles were used for separation and concentration of flavonoids from fruit extracts by a forced-adsorption dispersive solid phase extraction method. The combined use of this nanoparticle and our experimental conditions showed excellent precision (3.6–4.7%) and sensitivity (limits of detection (S/N=3): 0.6–3.75 ng/mL). This research provides an alternative strategy to prepare suitable sorbents for adsorption, separation and concentration of various compounds from different extracts.
Co-reporter:Man Wang;Xiaodi Yang
Journal of Separation Science 2015 Volume 38( Issue 3) pp:445-452
Publication Date(Web):
DOI:10.1002/jssc.201400991
Magnetic graphitic carbon nitride nanocomposites were successfully prepared in situ and used to develop a highly sensitive magnetic solid-phase extraction method for the preconcentration of phthalate esters such as di-n-butyl phthalate, butyl phthalate, dihexyl phthalate, and di-(2-ethyl hexyl) phthalate from water. The adsorption and desorption of the phthalate esters on magnetic graphitic carbon nitride nanocomposites were investigated and the parameters affecting the partition of the phthalate esters, such as adsorption, desorption, recovery, were assessed. Under the optimized conditions, the proposed method showed excellent sensitivity with limits of detection (S/N = 3) in the range of 0.05–0.1 μg/L and precision in the range of 1.1–2.6% (n = 5). This method was successfully applied to the analysis of real water samples, and good spiked recoveries over the range of 79.4–99.4% were obtained. This research provides a possibility to apply this nanocomposite for adsorption, preconcentration, or even removal of various carbon-based ring or hydrophobic pollutants.
Co-reporter:Wentao Bi;Man Wang;Xiaodi Yang;Kyung Ho Row
Journal of Separation Science 2014 Volume 37( Issue 13) pp:1632-1639
Publication Date(Web):
DOI:10.1002/jssc.201400142
Poly(ionic liquid)-bonded magnetic nanospheres were easily synthesized and applied to the pretreatment and determination of phenolic compounds in water samples, which have detrimental effects on water quality and the health of living beings. The high affinity of poly(ionic liquid)s toward the target compounds as well as the magnetic behavior of Fe3O4 were combined in this material to provide an efficient and simple magnetic solid-phase extraction approach. The adsorption behavior of the poly(ionic liquid)-bonded magnetic nanospheres was examined to optimize the synthesis. Different parameters affecting the magnetic solid-phase extraction of phenolic compounds were assessed in terms of adsorption and recovery. Under the optimal conditions, the proposed method showed excellent detection sensitivity with limits of detection in the range of 0.3–0.8 ng/mL and precision in the range of 1.2–3.3%. This method was also applied successfully to the analysis of real water samples; good spiked recoveries over the range of 82.5–99.2% were obtained.
Co-reporter:Dandan Li, Jun Zhu, Man Wang, Wentao Bi, Xiaohua Huang, David Da Yong Chen
Journal of Chromatography A (31 March 2017) Volume 1491() pp:27-35
Publication Date(Web):31 March 2017
DOI:10.1016/j.chroma.2017.02.048
Co-reporter:Shanshan Fan, Jun Zhu, Lixuan Ren, Man Wang, Wentao Bi, Huihui Li, Xiaohua Huang, David Da Yong Chen
Analytica Chimica Acta (1 April 2017) Volume 960() pp:
Publication Date(Web):1 April 2017
DOI:10.1016/j.aca.2017.01.020
•Magnetic velvet-like graphitic carbon nitride was used for rapid 1 min SPE.•Co-solvent enhanced adsorption of MSPE by changing solvent environment.•Synergistic effects improved the MSPE efficiency with excellent reproducibility.Magnetic velvet-like graphitic carbon nitride (V-g-C3N4/Fe3O4) was used for rapid 1 min extraction of flavonoids from different tea extracts by co-solvent enhanced adsorptive magnetic solid phase extraction. The nanocomposite can interact with flavonoids, in which Fe3O4 provide hydrogen bond and V-g-C3N4 has hydrophobic and π-π interaction to promote adsorption. The enhanced adsorptive magnetic solid phase extraction method is developed with the addition of a co-solvent (water) to dramatically change the solvent environment, which enhanced the speed of movement of target compounds from the solvent to the sorbent and increase the adsorption capacity. The synergistic effects improved the extraction rate of flavonoids with excellent reproducibility (88.2–107.2%), sensitivity (limits of detection (S/N = 3): 0.075–0.1 μg/mL) and recoveries (88.2–107.2%). This study demonstrated the potential to apply this method for various target analytes from complex sample matrices.
