The palladium-catalyzed Suzuki cross-coupling of phenylhydrazine or (phenylsulfonyl)hydrazine was developed for the preparation of biaryl compound in high yields. Moreover, these hydrazines were also used in other cross-coupling reactions, and a possible pathway of this reaction was examined.

A highly efficient protocol for regioselective synthesis of diaryl ketones by palladium-catalyzed direct acylation of arenes using thioethers as directing groups is reported. The possible pathway of direct acylation between thioethers and α-oxocarboxylic acids is discussed.

A new efficient method for the direct alkenylation of 3-arylsydnones by palladium-catalyzed C–H functionalization was developed. The reaction proceeded smoothly at room temperature and delivered the product in yields up to 83 %.

An efficient route for the synthesis of 2,4-disubstituted 1,2,3-triazoles by the regioselective direct arylation of 2-aryl-1,2,3-triazole N-oxides with Ar–X [X = Br, I and B(OH)₂] is demonstrated. The reaction proceeds through Pd-catalyzed C–H bond activation, and the influence of the aryl halides on the reactivity is investigated.

A mild and efficient method for the direct alkenylation of 5-pyrazoles by Pd-catalyzed C–H bond activation is described. The reaction smoothly proceeds at room temperature to provide products in up to 92 % yield.

1-Monosubstituted aliphatic 1,2,3-triazoles were synthesized by a one-pot reaction from aliphatic halides (Cl and Br), sodium azide and propiolic acid. The yields ranged from moderate to good. The reaction was easily carried out in DMF with Cs₂CO₃ at 100°C by copper-catalyzed click cycloaddition/decarboxylation.

A new methodology for the Cu-catalyzed synthesis of 1H-1,2,3-triazoles from 1,1-dibromoalkenes and sodium azide is presented. Aryl dibromoolefins were efficiently converted into the corresponding 1,2,3-triazoles. A comprehensive number of functional groups were compatible with this reaction. 1,2,3-Triazoles were obtained in moderate to excellent yields.

Symmetrical diynes were synthesized by ligand-free copper-catalyzed homocoupling reaction of 1,1-dibromo-1-alkenes using a DBU/DMSO system at room temperature in good to excellent yields dot.⁻¹.

A convenient, efficient, and generally applicable method was developed for the synthesis of terminal alkynes from anti-3-aryl-2,3-dibromopropanoic acids in the presence of DMSO and K₂CO₃.

A novel method for the stereoselective synthesis of (Z)-4-(2-bromovinyl)benzenesulfonyl azide by simultaneous azidation and debrominative decarboxylation of anti-2,3-dibromo-3-(4-chlorosulfonylphenyl)propanoic acid using NaN₃ only was developed. Facile transformation of (Z)-4-(2-bromovinyl)benzenesulfonyl azide to (Z)-N-[4- (2-bromovinyl)benzenesulfonyl]imidates was also achieved by Cu-catalyzed three-component coulping of (Z)-4-(2-bromovinyl)benzenesulfonyl azide, terminal alkynes and alcohols/phenols.