Co-reporter:Jianquan Weng, Zhiqin Yu, Xinghai Liu, Guofu Zhang
Tetrahedron Letters 2013 Volume 54(Issue 10) pp:1205-1207
Publication Date(Web):6 March 2013
DOI:10.1016/j.tetlet.2012.12.059
Direct oxidative ortho-acylation reaction of anilides with toluene derivatives in the presence of palladium acetate using tert-butyl hydroperoxide as an oxidant was developed. A broad range of diaryl ketones was obtained in good to excellent yields (up to 95%). The plausible mechanism was also proposed.