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Paul Reider

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Organization: Princeton University
Department: Department of Chemistry, Frick Chemical Laboratory
Title:
A Concise and Convergent Synthesis of PA-824
Co-reporter:Maurice A. Marsini, Paul J. Reider, and Erik J. Sorensen
The Journal of Organic Chemistry 2010 Volume 75(Issue 21) pp:7479-7482
Publication Date(Web):October 7, 2010
DOI:10.1021/jo1015807
An efficient four-step synthesis of PA-824, a promising antituberculosis drug candidate, has been developed. This concise approach offers significant improvements over the synthetic route currently used for large-scale production.
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