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Nan Wang

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Organization: Chinese Academy of Sciences
Department: Institute of Applied Ecology
Title:
Nine new diterpenes from the leaves of plantation-grown Cunninghamia lanceolata
Co-reporter:Shuangshuang Zhao, Junhong Ling, Zhanlin Li, Silong Wang, Jiangchun Hu, Nan Wang
Bioorganic & Medicinal Chemistry Letters 2015 Volume 25(Issue 7) pp:1483-1489
Publication Date(Web):1 April 2015
DOI:10.1016/j.bmcl.2015.02.026
Nine new diterpenes named lanceolatanol hydroperoxide (1), epilanceolatanol hydroperoxide (2), lanceolatanoic acid hydroperoxide (3), epilanceolatanoic acid hydroperoxide (4), lanceolatanol (5), lanceolatanoic acid (6), 11-acetoxylanceolatanoic acid (7), 11-acetoxylanceolatanoic acid methyl ester (8) and epoxyhinokiol (13) were characterized from the leaves of plantation-grown Cunninghamia lanceolata along with twelve known compounds. The compounds were evaluated for their growth inhibitory activities against the human prostate cell line (PC-3).
Cytotoxic Polyphenols from a Sponge-Associated Fungus Aspergillus versicolor Hmp-48
Co-reporter:Xiao Wang;Yanhua Mou;Jiangchun Hu;Li Zhao;Li Liu;Shujin Wang;Dali Meng
Chemistry & Biodiversity 2014 Volume 11( Issue 1) pp:133-139
Publication Date(Web):
DOI:10.1002/cbdv.201300115

Abstract

A new dibenzo[1,4]dioxin 1, and two new prenylated diphenyl ethers, 2 and 3, together with six known compounds, 4–9, were isolated from a sponge-associated fungus Aspergillus versicolor Hmp-F48 by bioactivity-guided fractionation. Their structures were elucidated by 1D- and 2D-NMR, and MS analyses. The compounds showed potent cell growth inhibitory activities against HL-60 cell line.

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2-Butenedioic acid(2E)-,1-[(2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethyl)-2H-pyran-4-yl]ester
2-Butenedioic acid(2E)-,1-[(2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethyl)-2H-pyran-4-yl]ester
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2-Butenedioic acid(2E)-,1-[(2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethyl)-2H-pyran-4-yl]ester
2-Butenoicacid, 4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-4-oxo-,(2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethyl)-2H-pyran-4-ylester, (2E)-
2-Butenoicacid, 4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-4-oxo-,(2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethyl)-2H-pyran-4-ylester, (2E)-
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2-Butenoicacid, 4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-4-oxo-,(2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethyl)-2H-pyran-4-ylester, (2E)-
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(1R,4aR,5S,8aR)-1,4a-Dimethyl-6-methylene-5-[(2E)-3-methyl-2,4-pe ntadien-1-yl]decahydro-1-naphthalenecarboxylic acid
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3,3'-oxybis(5-methylbenzene-1,2-diol)
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Me ester-2-Hydroxy-4-(3-hydroxy-5-methylphenoxy)-6-methylbenzoic acid
(7'Z)-7'-ETHYLIDENE-6-HYDROXY-1-METHOXYSPIRO[INDOLE-3,2'-[11]OXA[5]AZATRICYCLO[6.3.1.0<SUP>4,9</SUP>]DODECAN]-2(1H)-ONE
(7'Z)-7'-ETHYLIDENE-6-HYDROXY-1-METHOXYSPIRO[INDOLE-3,2'-[11]OXA[5]AZATRICYCLO[6.3.1.0<SUP>4,9</SUP>]DODECAN]-2(1H)-ONE
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(7'Z)-7'-ETHYLIDENE-6-HYDROXY-1-METHOXYSPIRO[INDOLE-3,2'-[11]OXA[5]AZATRICYCLO[6.3.1.04,9]DODECAN]-2(1H)-ONE
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5,7-dihydroxy-8-[2-hydroxy-5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)phenyl]-2-(4-hydroxyphenyl)-4-benzopyrone
Neocryptomerin
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Neocryptomerin