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Donald Hilvert

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Name: Hilvert, Donald
Organization: Laboratory of Organic Chemistry , USA
Department:
Title: Adjunct(PhD)
Tailor-Made Peptide Synthetases
Co-reporter:Hajo Kries, Donald Hilvert
Chemistry & Biology 2011 Volume 18(Issue 10) pp:1206-1207
Publication Date(Web):28 October 2011
DOI:10.1016/j.chembiol.2011.10.006
Harnessing the modular architecture of non-ribosomal peptide synthetases for combinatorial biosynthesis is a longstanding goal in chemical biology. Several recent reports illustrate how computational design and directed evolution can be used to tailor the specificity of these assembly-line enzymes.
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