An efficient method has been developed for the cascade synthesis of azo[l,2-a]indolones from azoles and 2-fluoroaldehydes based on an iron-catalyzed SNAr and a direct acylation reaction. A number of azo[l,2-a]indolones containing different azole rings and substituents were obtained in good yields.An efficient method has been developed for the cascade synthesis of azo[l,2-a]indolones from azoles and 2-fluoroaldehydes based on an iron-catalyzed SNAr and a direct acylation reaction.

In this study, a one-pot, phosphine/palladium sequential catalysis reaction has been realized, and a series of functionalized alkenyl 6H-benzo[c]chromenes are synthesized in high yields and with good stereoselectivity.

Propylamine modified with imidazolium ionic moiety grafted onto magnetic nanoparticles (MNPs) was prepared and evaluated as a catalyst for Knoevenagel condensation in water at room temperature. The catalyst was efficient in the reaction to give the condensation products in good yields. It is worth noting that the ionic-tagged catalyst performed significantly better than its ionic tag-free counterpart. Finally, the catalyst could be reused for 8 times with a slight loss in its catalytic activity.

A stereo-selective reaction for the synthesis of cis-alkenes/halo-alkenes from diphenylmethane and ethynylbenzenes was developed in the presence of iron(III) bromide or chloride. Alkenyl bromides/chlorides were obtained in comparatively good yields in chlorobenzene under mild reaction conditions.

An efficient CuBr catalyzed cleavage of C–N bonds in the oxidative cross-dehydrogenative-coupling (CDC) of N-benzyl amines with indoles mediated by tert-butyl hydroperoxide (TBHP) was reported. A series of methine-bridged bis-indole derivatives were successfully synthesized under the optimized reaction conditions.

An efficient CuBr catalyzed cleavage of C–N bonds in the oxidative cross-dehydrogenative-coupling (CDC) of N-benzyl amines with indoles mediated by tert-butyl hydroperoxide (TBHP) was reported. A series of methine-bridged bis-indole derivatives were successfully synthesized under the optimized reaction conditions.