Wei Deng

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Organization: University of Science and Technology of China
Department: Research Center of Nano Science and Technology
Title:
Co-reporter:Shibin Hong, Mengyan Liu, Wei Zhang, Qiang Zeng, Wei Deng
Tetrahedron Letters 2015 Volume 56(Issue 18) pp:2297-2302
Publication Date(Web):29 April 2015
DOI:10.1016/j.tetlet.2015.03.033
A mild method has been developed for the hydroboration of arylalkenes using Cu2O as catalyst with PPh3 as ligand in methanol at room temperature. A gram-scale reaction under this condition was also achieved with high yield.
Co-reporter:Meng-Yan Liu, Shi-Bin Hong, Wei Zhang, Wei Deng
Chinese Chemical Letters 2015 Volume 26(Issue 3) pp:373-376
Publication Date(Web):March 2015
DOI:10.1016/j.cclet.2014.12.004
Amino acids were found to be as good ligands for copper-catalyzed borylation reactions of primary and secondary alkyl halides, and the B2pin2 acted as bi-boron source for borylation. The high reaction efficiency and mild conditions make the new catalyst system a useful alternative to the recently developed methods for the preparation of alkylboronic esters.A highly general, experimentally simple, and inexpensive catalyst system was developed for copper-catalyzed borylation reactions of primary and secondary alkyl halides with amino acid as ligand.
Propanoic acid, 3-(methylamino)-3-thioxo-, methyl ester
(E)-2-(2-Chlorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
(E)-2-(4-Bromostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
2-(4-(tert-Butyl)phenethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
2-[2-(4-fluorophenyl)ethyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane