Hui Yu

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Name: 于辉; Hui Yu

Organization: Key Laboratory of Yangtze River Water Environment , China

Department: Department of Chemistry

Title: Associate Professor(PhD)

TOPICS

Organic Chemistry

Chemicals
References

NH4I-Catalyzed Synthesis of Sulfonamides from Arylsufonylhydrazides and Amines

Co-reporter:Hui Yu;Yonghao Zhang

Chinese Journal of Chemistry 2016 Volume 34( Issue 4) pp:359-362

Publication Date(Web):

DOI:10.1002/cjoc.201500796

Abstract

A novel and efficient approach to sulfonamides has been developed. Using TBHP as the oxidant and NH₄I (20 mol%) as the catalyst, arylsulfonyl hydrazides reacted with amines to provide sulfonamides in moderate to good yields. Possible reaction pathway for the formation of the products was also discussed in this paper.

Dehydrogenative cyclization of N-acyl dipeptide esters for the synthesis of imidazolidin-4-ones

Co-reporter:Hui Yu and Jie Shen

RSC Advances 2015 vol. 5(Issue 13) pp:9815-9818

Publication Date(Web):06 Jan 2015

DOI:10.1039/C4RA15019H

A dehydrogenative cyclization reaction for the synthesis of imidazolidin-4-ones was developed under mild conditions. Using tert-butyl hydroperoxide as oxidant and potassium iodide as catalyst, N-acyl dipeptide esters were converted to imidazolidin-4-ones in an atom-economical intramolecular C–N bond formation process in good yields.

Copper-Catalyzed Synthesis of Imides from Aldehydes or Alcohols and Amine Hydrochloride Salts

Co-reporter:Hui Yu;Yonghao Zhang

European Journal of Organic Chemistry 2015 Volume 2015( Issue 8) pp:1824-1828

Publication Date(Web):

DOI:10.1002/ejoc.201403624

Abstract

An efficient approach to imides has been developed. With tert-butyl hydroperoxide (TBHP) as the oxidant, CuBr (20 mol-%) as the catalyst, and PhI(OAc)₂ (50 mol-%) as the additive, aldehydes or alcohols reacted with amine hydrochloride salts to provide imides in moderate to good yields. A possible reaction pathway for the formation of the products is also discussed in this paper.

TBHP/TEMPO-Mediated Oxidative Synthesis of Imides from Amides

Co-reporter:Hui Yu;Yuegang Chen;Yonghao Zhang

Chinese Journal of Chemistry 2015 Volume 33( Issue 5) pp:531-534

Publication Date(Web):

DOI:10.1002/cjoc.201500190

Abstract

A new protocol for the synthesis of imides has been developed. In the presence of copper catalyst, N-benzylamides were oxidized to the corresponding imides by TBHP/TEMPO system in moderate to good yields.

Peroxidation of C–H Bonds Adjacent to an Amide Nitrogen Atom under Mild Conditions

Co-reporter:Hui Yu and Jie Shen

Organic Letters 2014 Volume 16(Issue 12) pp:3204-3207

Publication Date(Web):June 3, 2014

DOI:10.1021/ol5012168

Under mild conditions, the oxidative functionalization of C–H bonds adjacent to an amide nitrogen atom was achieved. tert-Butylperoxyamido acetal was obtained in high yields and could be further converted into α-substituted amides by treatment with Grignard reagents.

Metal-Free Oxidative Cyclization of o-Acylphenols for the Construction of 2-Aminobenzofuran-3(2H)-ones

Co-reporter:Hui Yu;Weihua Huang ;Fengling Zhang

European Journal of Organic Chemistry 2014 Volume 2014( Issue 15) pp:3156-3162

Publication Date(Web):

DOI:10.1002/ejoc.201301756

Abstract

An efficient metal-free approach to the synthesis of 2-aminobenzofuran-3(2H)-ones has been developed. Using TBHP as an oxidant and I₂ (or TBAI) as catalyst, 2-acylphenols were treated with secondary amines to provide 2-aminobenzofuran-3(2H)-one derivatives in moderate to good yields. A possible reaction pathway for the formation of 2-dimorpholinobenzofuran-3(2H)-one is also discussed herein.

Copper-Catalyzed Synthesis of Benzo[b]thiophenes and Benzothiazoles Using Thiocarboxylic Acids as a Coupling Partner

Co-reporter:Hui Yu, Meishu Zhang, and Yuzhe Li

The Journal of Organic Chemistry 2013 Volume 78(Issue 17) pp:8898-8903

Publication Date(Web):August 19, 2013

DOI:10.1021/jo401353w

An efficient copper-catalyzed approach to benzo[b]thiophene and benzothiazole derivatives using thiocarboxylic acids as a sulfur source has been developed. In the presence of CuI and 1,10-phen, and n-Pr3N as the base, (2-iodobenzyl)triphenylphosphonium bromide and (2-iodophenylimino)triphenylphosphorane reacted smoothly with thiocarboxylic acids to give benzo[b]thiophene and benzothiazole derivatives in good yields via sequential Ullmann-type C–S bond coupling and Wittig condensation.

Copper-catalyzed synthesis of 1,2-disubstituted benzimidazoles from imidoyl chlorides

Co-reporter:Hui Yu, Mei Shu Zhang, Li Ren Cui

Chinese Chemical Letters 2012 Volume 23(Issue 5) pp:573-575

Publication Date(Web):May 2012

DOI:10.1016/j.cclet.2012.02.008

A strategy for the synthesis of 1,2-disubstituted benzimidazoles has been developed and a variety of 1,2-disubstituted benzimidazoles were obtained from imidoyl chlorides and o-haloanilines via copper(I)-catalyzed reaction in moderate yields.

Synthesis of 2-aminooxazolines from isonitriles and iodine

Co-reporter:Hui Yu, Yu Zhe Li, Qiong Liu, Mei Shu Zhang, Wen Liang Sun

Chinese Chemical Letters 2012 Volume 23(Issue 2) pp:130-132

Publication Date(Web):February 2012

DOI:10.1016/j.cclet.2011.09.017

A novel one-pot protocol for the synthesis of substituted 2-aminooxazoline from isonitriles and 2-aminoethanol was developed and the reactions involved imidoyl diiodide intermediates, which were generated by mixing isonitriles and iodine in CH2Cl2 at room temperature.

Radical reduction of Passerini 3CR adducts by SmI2/HMPA

Co-reporter:Hui Yu, Tao Gai, Wen Liang Sun, Mei Su Zhang

Chinese Chemical Letters 2011 Volume 22(Issue 4) pp:379-381

Publication Date(Web):April 2011

DOI:10.1016/j.cclet.2010.11.013

The Passerini 3-CR adducts of substituted cinnamaldehydes, isocyanides and acetic acid were treated with SmI2/HMPA in dry tetrahydrofuran (THF) at room temperature, and β,γ-unsaturated amides were obtained in moderate yields. The reaction was supposed involving a radical reduction procedure.