Robert Buchanan

Name:

Organization: University of Louisville

Department: Department of Chemistry

Title:

Chemicals
References

N-(2-formyl-1-methylimidazol-4-yl)-2,2-dimethylpropanamide: a versatile reagent for preparing imidazole-amine ligands with variable second-coordination spheres

Co-reporter:Lionel E. Cheruzel, Jinlan Cui, Mark S. Mashuta, Craig A. Grapperhaus, Robert M. Buchanan

Tetrahedron Letters 2011 Volume 52(Issue 37) pp:4771-4774

Publication Date(Web):14 September 2011

DOI:10.1016/j.tetlet.2011.07.025

Two synthetic pathways to N-(2-formyl-1-methylimidazol-4-yl)-2,2-dimethylpropanamide from 1-methyl-2-carboxaldehyde are described. The reagent serves as a useful synthon for reductive amination reactions with primary and secondary amines in the presence of sodium cyanoborohydride to yield a series of ligands with second coordination sphere functional groups. Protocols for the syntheses of related imidazole synthons functionalized in the 4-position with amino acids, Schiff bases, and other amides are also reported.

A supramolecular assembly of side-by-side polyimidazole tripod coils stabilized by π–π stacking and unique boric acid templated hydrogen bonding interactions

Co-reporter:Lionel E. Cheruzel, Mark S. Mashuta and Robert M. Buchanan

Chemical Communications 2005 (Issue 17) pp:2223-2225

Publication Date(Web):11 Mar 2005

DOI:10.1039/B419040H

The self assembly of (bis(1-methyl-imidazol-2-yl)methyl)(1-methyl-4-nitroimidazol-2-yl)methyl)amine and boric acid results in a supramolecular structure containing bundled antiparallel imidazole-boric acid helices and boric acid filled one-dimensional channels.

Structures and Solid-State Dynamics of One-Dimensional Water Chains Stabilized by Imidazole Channels

Co-reporter:Lionel E. Cheruzel;Maxim S. Pometun;Matthew R. Cecil;Mark S. Mashuta Dr.;Richard J. Wittebort Dr.;Robert M. Buchanan Dr.

Angewandte Chemie International Edition 2003 Volume 42(Issue 44) pp:

Publication Date(Web):6 OCT 2003

DOI:10.1002/anie.200352157

Proton wires: One-dimensional water chains play an important role in proton permeation through transmembrane proteins. The X-ray crystal structures as well as solid-state ²H and ¹⁷O NMR and calorimetry studies of two imidazole hydrates that stabilize infinite one-dimensional water chains are reported (see picture; N blue, O red, H white). The ²H NMR spectroscopic studies suggest that water molecules in both compounds undergo different reorientational dynamics.

Structures and Solid-State Dynamics of One-Dimensional Water Chains Stabilized by Imidazole Channels

Co-reporter:Lionel E. Cheruzel;Maxim S. Pometun;Matthew R. Cecil;Mark S. Mashuta Dr.;Richard J. Wittebort Dr.;Robert M. Buchanan Dr.

Angewandte Chemie 2003 Volume 115(Issue 44) pp:

Publication Date(Web):6 OCT 2003

DOI:10.1002/ange.200352157

Protonenleiter: Ketten aus Wassermolekülen spielen eine wichtige Rolle bei der Permeation von Protonen durch Transmembranproteine. Berichtet wird über die Kristallstrukturen, ²H- und ¹⁷O-Festkörper-NMR-Spektren und kalorimetrische Untersuchungen zweier Imidazolhydrate, die endlose eindimensionale Ketten aus Wassermolekülen stabilisieren (siehe Bild; N blau, O rot, H weiß). Die ²H-NMR-Spektren weisen auf eine unterschiedliche Umorientierungsdynamik der Wassermoleküle in beiden Verbindungen hin.

Structure and properties of an Fe(III) complex containing a novel amide functionalized polyimidazole ligand

Co-reporter:Lionel E. Cheruzel, Jianping Wang, Mark S. Mashuta and Robert M. Buchanan

Chemical Communications 2002 (Issue 18) pp:2166-2167

Publication Date(Web):23 Aug 2002

DOI:10.1039/B204799C

A novel amide functionalized polyimidazole tripod ligand has been synthesized and used to prepare a mononuclear Fe(III) complex that has been characterized by X-ray crystallography and other physical methods.

butane-2,3-dione bis(N-methylthiosemicarbazone)

CAS:63618-91-7

butane-2,3-dione bis(N-methylthiosemicarbazone)

CAS:75-05-8

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