To improve the conductivity of anion exchange membranes without reducing the mechanical properties, a series of poly ionic liquids (PILs) with precursors of 1,3,5-tris(1-imidazolyl)benzene (TIB) containing tri-conduct groups were synthesized and incorporated into quaternized poly (2,6-dimethyl phenylene oxide) (QPPO) membranes. The new poly ionic liquids we designed contain ternary conduct groups in one monomer which are advantageous to form ionic channels and thus dramatically increase the conductivity of membranes. Various alkyl chains were introduced into TIB during polymerization to tune the distance between two tri-conduct groups. The resulting PILs/QPPO composite membranes showed good thermal stability, appropriate mechanical properties, enhanced conductivity and fuel cell performance. When the numbers of –CH2– between two tri-conduct groups reached 12, the composite membrane showed the highest conductivity and fuel cell performance (55.5 mS/cm at 80 °C and 168.9 mW/cm2). The composite membranes we prepared show potential application in anion exchange membrane fuel cells (AEMFCs).

The development of efficient bioorthogonal reactions for sensing of endogenous biomolecules and for bioconjugation should be of paramount importance in the field of chemical biology. In this work, the o,o′-difluorinated aromatic azide was firstly employed to develop a new fast-response fluorescent probe 1 for H2S detection and for bioorthogonal reactions. Compared with non- and mono-fluorinated probes, 1 showed faster reaction toward H2S, the third gasotransmitter, in buffer (pH 7.4), implying that the reaction rate could be enhanced by the dual-fluorine groups. Furthermore, such enhanced reaction rates of 1 were also observed in the Staudinger reaction and strain-promoted azide–alkyne cycloaddition (SPAAC) based on the comparison studies of the non-fluorinated probe. Our results firstly highlight that the o,o′-difluorinated aromatic azide group should be useful for fast bioorthogonal reactions and H2S detection.

•Acylphosphines as the novel phosphorus source for Pd-catalyzed C–P bond formation.•Direct syntheses of trivalent phosphines.•Acylphosphines employed as suitable ligands to Pd as well.•The addition of Cs2CO3 promoted the reaction.•The plausible mechanism was proposed.Palladium-catalyzed C–P(III) bond formation reaction employing acylphosphines as the phosphorus source was developed. Under the optimized conditions, acylphosphines could react with aryl halides directly affording trivalent phosphines in up to 94% yield.

•Synthesis of a series of 8-alkoxy-6-alkylamino-2-alkylthiopurine nucleosides.•Differentiate the 2-, 6-, and 8-positions of similar reactivity in nucleophilic substitution.•The sequence of alkylthiolation, alkoxylation, and amination facilitated the synthesis.A straight forward strategy to synthesize purine nucleosides with multiple functionalization on 2-, 6-, and 8-positions has been developed successfully, which provides a series of 8-alkoxy-6-alkylamino-2-alkylthiopurine nucleosides in moderate to good yields for further biological and medical activity screening.Download high-res image (111KB)Download full-size image

Acylphosphines, which could be efficiently prepared from acid chlorides and secondary phosphines, were developed as a type of carbonyl group tuned electron-deficient phosphorus ligand. They were found to be a kind of efficient ligand in Rhodium catalyzed arylation to aldehydes through accelerating the transmetalation process. Chiral acylphosphine ligands could be generated from carboxylic acids bearing the chiral framework correspondingly.

The development of efficient bioorthogonal reactions for sensing of endogenous biomolecules and for bioconjugation should be of paramount importance in the field of chemical biology. In this work, the o,o′-difluorinated aromatic azide was firstly employed to develop a new fast-response fluorescent probe 1 for H2S detection and for bioorthogonal reactions. Compared with non- and mono-fluorinated probes, 1 showed faster reaction toward H2S, the third gasotransmitter, in buffer (pH 7.4), implying that the reaction rate could be enhanced by the dual-fluorine groups. Furthermore, such enhanced reaction rates of 1 were also observed in the Staudinger reaction and strain-promoted azide–alkyne cycloaddition (SPAAC) based on the comparison studies of the non-fluorinated probe. Our results firstly highlight that the o,o′-difluorinated aromatic azide group should be useful for fast bioorthogonal reactions and H2S detection.