Co-reporter: Ross M. Denton, James T. Scragg, Jan Saska
pp: 2554-2556
Publication Date(Web):18 May 2011
DOI: 10.1016/j.tetlet.2011.03.031
A concise and protecting group free synthesis of the naturally occurring neolignan 4′-O-methyl honokiol is developed. The key biaryl bond is constructed by 1,2-addition of an aryl Grignard reagent to a dienone followed by rearrangement.
