Co-reporter: I-Hon Chen, Motomu Kanai, and Masakatsu Shibasaki
pp: 4098-4101
Publication Date(Web):August 19, 2010
DOI: 10.1021/ol101691p
A copper(I)−chiral secondary diamine (L-e) complex catalyzes an enantioselective conjugate boration of β,β-disubstituted enones in high yields and up to 99% ee. Product chiral tertiary organoboronates can be converted to enantiomerically enriched cross-aldol products between ketones without any racemization.
