214219-69-9|2-Piperidinone,1-(1,2-propadien-1-yl)-

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Marc C. Kimber

Loughborough University

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A simple one-pot preparation of N-allenyl amides, ureas, carbamates and sulfonamides using a DMSO/tBuOK protocol

Co-reporter: Thomas W. Bousfield, Marc C. Kimber

pp: 350-352

Publication Date(Web):8 January 2015

DOI: 10.1016/j.tetlet.2014.11.093

A one-pot transformation of amides, ureas, carbamates and sulfonamides into synthetically useful N-allenyl analogues using a tBuOK/DMSO protocol is reported. The procedure is experimentally simple and robust, and provides N-allenyl analogues, commonly used within the literature, in yields comparable to the benchmark two-step approach. Image for unlabelled figure

Synthesis and solid state structure of pyridyl diboroxines linked by a chiral spacer analogous to Tröger’s base

Co-reporter: Mark R.J. Elsegood, Marc C. Kimber

pp: 346-349

Publication Date(Web):8 January 2015

DOI: 10.1016/j.tetlet.2014.11.094

Pyridyl-assisted templating of phenyl boronic acid has been utilised to link two remote boroxines via a chiral spacer. The chiral spacer is a carbocyclic analogue of Tröger’s base and contains a unique chiral cavity, and the flanking boroxine units have been shown, by single crystal X-ray analysis, to extend the size and shape of this cavity. Image for unlabelled figure

Jiangtao Sun

Changzhou University

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