Chao Liu

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Name: 刘超; Liu, Chao

Organization: Chinese Academy of Sciences , China

Department: Shanghai Institute of Organic Chemistry

Title: Associate Researcher(PhD)

TOPICS

Organic Chemistry

Chemicals
References

Oxidative decarboxylative radical trifluoromethylthiolation of alkyl carboxylic acids with silver(I) trifluoromethanethiolate and selectfluor

Co-reporter:Bin He;Zhiwei Xiao;Hao Wu;Yong Guo;Qing-Yun Chen

RSC Advances (2011-Present) 2017 vol. 7(Issue 2) pp:880-883

Publication Date(Web):2017/01/03

DOI:10.1039/C6RA26133G

A straightforward silver-mediated oxidative decarboxylative radical trifluoromethylthiolation reaction of aliphatic carboxylic acid is described. This reaction operates under mild conditions and allows the synthesis of various valuable alkyltrifluoromethylthioethers from abundant alkyl carboxylic acids and convenient nucleophilic AgSCF3 reagent. It provides a practical and efficient approach for the preparation of alkyltrifluoromethylthioethers.

Oxidative decarboxylative radical trifluoromethylthiolation of alkyl carboxylic acids with silver(I) trifluoromethanethiolate and selectfluor

Co-reporter:Bin He;Zhiwei Xiao;Hao Wu;Yong Guo;Qing-Yun Chen

RSC Advances (2011-Present) 2017 vol. 7(Issue 2) pp:880-883

Publication Date(Web):2017/01/03

DOI:10.1039/C6RA26133G

Trifluoromethylfluorosulfonylation of Unactivated Alkenes Using Readily Available Ag(O2CCF2SO2F) and N-Fluorobenzenesulfonimide

Co-reporter:Yongan Liu;Dr. Hao Wu; Dr. Yong Guo; Dr. Ji-Chang Xiao; Dr. Qing-Yun Chen; Dr. Chao Liu

Angewandte Chemie 2017 Volume 129(Issue 48) pp:15634-15637

Publication Date(Web):2017/11/27

DOI:10.1002/ange.201709663

AbstractPresented is a novel intermolecular radical trifluoromethylfluorosulfonylation of unactivated alkenes under mild reaction conditions with good functional-group tolerance in the most atom-economic manner by using readily available Ag(O2CCF2SO2F) and N-fluorobenzenesulfonimide (NFSI). Both the trifluoromethyl and sulfonyl groups in the products originate from Ag(O2CCF2SO2F).

Trifluoromethylfluorosulfonylation of Unactivated Alkenes Using Readily Available Ag(O2CCF2SO2F) and N-Fluorobenzenesulfonimide

Co-reporter:Yongan Liu;Dr. Hao Wu; Dr. Yong Guo; Dr. Ji-Chang Xiao; Dr. Qing-Yun Chen; Dr. Chao Liu

Angewandte Chemie International Edition 2017 Volume 56(Issue 48) pp:15432-15435

Publication Date(Web):2017/11/27

DOI:10.1002/anie.201709663

An optimized condition for practical and scalable hydrodeiodination of perfluoroalkyl iodides

Co-reporter:Junhui Wu, Zhen-Jiang Liu, Qing-Yun Chen, Chao Liu

Journal of Fluorine Chemistry 2016 Volume 184() pp:45-49

Publication Date(Web):April 2016

DOI:10.1016/j.jfluchem.2016.02.005

⿢A practical method for hydrodehalogenation of various perfluoroalkyl iodides and bromides under mild conditions is presented.⿢Substrates with base-sensitive groups can be smoothly subjected to the reaction.⿢Water as a co-solvent plays an important role in the reaction.An efficient and convenient synthesis of various hydroperfluoroalkanes from the corresponding perfluoroalkyl iodides or bromides with zinc powder in HOAc/H2O has been developed. The reaction is quite practical and suitable for large-scale preparation due to the simple experimental procedures and the readily available reagents.An efficient and convenient synthesis of various hydroperfluoroalkanes from the corresponding perfluoroalkyl halides has been developed. The reaction is quite practical and suitable for large-scale preparation due to the simple experimental procedures and the readily available reagents.

Direct Trifluoromethylthiolation of Unactivated C(sp3)H Using Silver(I) Trifluoromethanethiolate and Potassium Persulfate

Co-reporter:Hao Wu;Zhiwei Xiao;Junhui Wu;Dr. Yong Guo;Dr. Ji-Chang Xiao;Dr. Chao Liu;Dr. Qing-Yun Chen

Angewandte Chemie 2015 Volume 127( Issue 13) pp:4142-4146

Publication Date(Web):

DOI:10.1002/ange.201411953

Abstract

A practical and efficient method for the direct trifluoromethylthiolation of unactivated C(sp³)H bonds by AgSCF₃/K₂S₂O₈ under mild conditions is described. The reaction has a good functional-group tolerance and good selectivity. Initial mechanistic investigations indicate that the reaction may involve a radical process in which K₂S₂O₈ plays key roles in both the activation of the C(sp³)H bond and the oxidation of AgSCF₃.

Direct Trifluoromethylthiolation of Unactivated C(sp3)H Using Silver(I) Trifluoromethanethiolate and Potassium Persulfate

Co-reporter:Hao Wu;Zhiwei Xiao;Junhui Wu;Dr. Yong Guo;Dr. Ji-Chang Xiao;Dr. Chao Liu;Dr. Qing-Yun Chen

Angewandte Chemie International Edition 2015 Volume 54( Issue 13) pp:4070-4074

Publication Date(Web):

DOI:10.1002/anie.201411953

Abstract

A General, Regiospecific Synthetic Route to Perfluoroalkylated Arenes via Arenediazonium Salts with RFCu(CH3CN) Complexes

Co-reporter:Dong-Fang Jiang;Yong Guo;Ji-Chang Xiao ;Qing-Yun Chen

European Journal of Organic Chemistry 2014 Volume 2014( Issue 28) pp:6303-6309

Publication Date(Web):

DOI:10.1002/ejoc.201402820

Abstract

A mild method of converting arylamines into perfluoroalkylated arenes is described. Relatively stable R_FCu(CH₃CN) complexes are used as perfluoroalkylating agents, which react smoothly with arenediazonium salts to produce various perfluoroalkylarenes in good yields. Based on the results of clock trapping experiments with diallyl ether, a radical process might be involved in the reaction.