The novel polyol compounds, amdigenols E and G, were isolated from the dinoflagellate Amphidinium sp. that was found to adhere to the surface of the marine alga Digenea simplex. The structures of the two amdigenols were elucidated by NMR spectroscopy and ESI–CID-MS/MS analyses. Both amdigenols E and G shared partial structures with amdigenol A. Amdigenols E and G inhibited N-type Ca2+ channel-opening.

Three novel compounds, yoshinones A, B1, and B2, were isolated from the marine cyanobacterium Leptolyngbya sp., and their structures were elucidated by NMR spectral analysis. Yoshinone A, but not yoshinone B1 or B2, inhibited the differentiation of 3T3-L1 cells into adipocytes. In addition, yoshinone A did not exhibit cytotoxicity, suggesting that yoshinone A may be useful in studies on the treatment of obesity.

A polyol compound, amdigenol A, was isolated from the dinoflagellate Amphidinium sp. that adhered to the surface of the marine alga Digenea simplex. A structural elucidation was performed by 2D-NMR spectroscopy, degradation with a second generation Hoveyda–Grubbs catalyst and ESI-CID-MS/MS analyses. Amdigenol A consists of a C98-linear carbon backbone including two core structures of amphidinol analogs and is likely formed linearly by two amphidinol analogs.