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Wei-Dong Chen

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Name: 陈卫东; Chen, WeiDong
Organization: East China University of Science and Technology , China
Department: Shanghai Key Laboratory of Chemical Biology
Title: Assistant Researcher/Assistant Professor(PhD)
CuI-catalyzed intramolecular cyclization of 3-(2-aminophenyl)-2-bromoacrylate: synthesis of 2-carboxyindoles
Co-reporter:Xiong Xiao, Tian-Qi Chen, Jiangmeng Ren, Wei-Dong Chen, Bu-Bing Zeng
Tetrahedron Letters 2014 Volume 55(Issue 13) pp:2056-2060
Publication Date(Web):26 March 2014
DOI:10.1016/j.tetlet.2013.10.048
A new approach was described for the synthesis of substituted 2-carboxyindole using 3-(2-aminophenyl)-2-bromo-acrylates through a CuI-catalyzed intramolecular coupling. The reactions were mild, rapid and with good to excellent yields.
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