Co-reporter:Lai Bao Wang, Jia Pan, Can Ling Tang, Xiu Ren Bu, Jie Wang
Chinese Chemical Letters 2007 Volume 18(Issue 4) pp:390-392
Publication Date(Web):April 2007
DOI:10.1016/j.cclet.2007.02.015
Under regular heating and microwave irradiation, 3-alkyl substituted imidazo[1,5-a] pyridines were synthesized from 2,2′-pyridil, di-2-pyridyl ketone and aliphatic aldehydes in the presence of ammonium acetate and acetic acid. Compared to the traditional heating condition, the reaction time under microwave irradiation was shorter and 3-alkyl imidazo[1,5-a]pyridines were given in higher yield.