70577-96-7|2-Hexynoic acid, 4,4,5,5,6,6,6-heptafluoro-, methyl ester

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CAS: 70577-96-7

MF: C7H3O2F7

MW: 252.08632

Synonyms: 2-Hexynoic acid, 4,4,5,5,6,6,6-heptafluoro-, methyl ester

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Wei-Guo Cao

Shanghai University

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Three-component synthesis of 2-amino-3-cyano-5-oxo-4-perfluoroalkyl-5,6,7,8-tetrahydro-4H-chromene derivatives

Co-reporter: Linglin Bian, Jiechao Xu, Liqing Xie, Jie Chen, Hongmei Deng, Min Shao, Tianling Ding, Hui Zhang, Weiguo Cao

pp: 6121-6128

Publication Date(Web):

DOI: 10.1016/j.tet.2013.05.053

An efficient one-pot two-step three-component process for the synthesis of perfluoroalkylated biphenyls

Co-reporter: Yuhong Xu, Jing Han, You Lv, Renming Pan, Jie Chen, Hongmei Deng, Min Shao, Hui Zhang, Weiguo Cao

pp: 820-825

Publication Date(Web):4 February 2015

DOI: 10.1016/j.tet.2014.12.051

A practical and economical process for the synthesis of perfluoroalkylated biphenyl derivatives has been developed. The three-component reaction of aromatic ketones, malononitrile and methyl perfluoroalk-2-ynoates gave the desired products in good to excellent yields via a one-pot two-step process. Image for unlabelled figure

2-Hexynoic acid, 4,4,5,5,6,6,6-heptafluoro-, methyl ester

REPORT BY

Wei-Guo Cao

MinJie Li

Xiaoyu Wu

Li Li

Weiqi Tong

Jie Chen