Co-reporter: Dong-Fen Luo, Jun Xu, Yao Fu, Qing-Xiang Guo
pp: 2769-2772
Publication Date(Web):30 May 2012
DOI: 10.1016/j.tetlet.2012.03.107
A copper-catalyzed method for trifluoromethylation of terminal alkynes with Umemoto’s reagent has been developed. The reaction is conducted at room temperature and shows good tolerance to a variety of functional groups.