Benzenebutanoic acid, a-hydroxy-

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CAS: 4263-93-8
MF: C10H12O3
MW: 180.20048
Synonyms: Benzenebutanoic acid, a-hydroxy-

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Mo-Zhen Wang

University of Science and Technology of China and USTC-CityU Joint Advanced Research Center
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Peiran Chen

Donghua University
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Jack D Henion

Cornell University
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Co-reporter: Hoang V. Le, Lijun Fan, Bruce Ganem
pp: 2209-2211
Publication Date(Web):27 April 2011
DOI: 10.1016/j.tetlet.2010.11.156
N-tert-Butylamides are readily converted into the corresponding carboxylic acids by simple nitrosation. The process, which occurs under mild nonaqueous conditions, leaves carboxylic esters untouched and transforms multicomponent reaction products into useful building blocks for further synthetic elaboration.Image for unlabelled figure

Kazuaki Ishihara

Nagoya University
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Yoshihiko Yamamoto

Nagoya University
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