1,3-DIMETHYL-5-(4-METHYLPHENYL)BENZENE

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CAS: 7383-87-1
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Synonyms: 1,3-DIMETHYL-5-(4-METHYLPHENYL)BENZENE

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Xiu-Feng Hou

Fudan University
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Arnold L Rheingold

University of California
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Adam J. Matzger

The University of Michigan
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Han Vinh Huynh

National University of Singapore
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Kin Shing Chan

The Chinese University of Hong Kong
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Co-reporter: Ching Tat To, Tek Long Chan, Bao Zhu Li, Ying Ying Hui, TSZ Yiu Kwok, Suet Yu Lam, Kin Shing Chan
pp: 1023-1026
Publication Date(Web):2 March 2011
DOI: 10.1016/j.tetlet.2010.12.092
A general procedure for cobalt-catalyzed direct C–H arylation of unactivated arenes has been discovered. This method employs aryl halides as the direct coupling partners with arenes without using any Grignard-type reagents. This catalysis opens a new methodology for the preparation of symmetrical as well as unsymmetrical biaryls in a user-friendly approach.Image for unlabelled figure

Fuk Yee Kwong

The Hong Kong Polytechnic University
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Chau Ming So

The Hong Kong Polytechnic University
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Jared Lewis

The University of Chicago
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