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1H-1,2,3-Triazole-4-methanamine, 1-(phenylmethyl)-N,N-bis[[1-(phenylmethyl)-1H-1,2,3-triazol-4-yl]methyl]-

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CAS: 510758-28-8
MF: C30H30N10
MW: 530.6262
Synonyms: 1H-1,2,3-Triazole-4-methanamine, 1-(phenylmethyl)-N,N-bis[[1-(phenylmethyl)-1H-1,2,3-triazol-4-yl]methyl]-
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Hiroyuki Isobe

Tohoku University
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Efficient and improved synthesis of triazole-linked DNA (TLDNA) oligomers
Co-reporter: Tomoko Fujino, Naomi Yamazaki, Ai Hasome, Kenta Endo, Hiroyuki Isobe
pp: 868-870
Publication Date(Web):15 February 2012
DOI: 10.1016/j.tetlet.2011.12.026
A method for the synthesis of triazole-linked DNA oligomers has been revisited to incorporate a reliable protective group and linker for solid-phase synthesis. The new solid-phase synthesis allowed the preparation of oligomers with the efficiency of elongation reaching over 90%.Image for unlabelled figure

Kunio Awaga

Nagoya University
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Derek Macmillan

University College London
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Eleanor E. B. Campbell

University of Gothenburg
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Alison N. Hulme

The University of Edinburgh
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Matthew I. Gibson

University of Warwick
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Andrew Benniston

Newcastle University
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Jerry Hagon

Newcastle University
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WOHLAND Thorsten

NUS
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Omar K. Farha

Northwestern University
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